Gamers spend a lot of time on their desktop computers when playing online games. Since most of them require continuous mouse use, the best vertical mouse for gaming would be necessary.

Today we will have the chance to share our knowledge about the most explicit vertical gaming mouse models available on the market.

Let’s check the mouse peripherals that have changed gamers’ lives and let them live a lot better without any painful wrist syndromes!

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    Best Vertical Gaming Mouse


    QUICK OVERVIEW: Best Vertical Mouse

    51j0zidX0VL. AC SL1364 2
    • 800 / 1200 / 1600 DPI
    • Healthy neutral "handshake" wrist position
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    Jelly Comb Advanced
    • Bluetooth & 2.4G wireless connection
    • Silent click & adjustable DPI
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    Jelly Comb
    • High Responsiveness: 800 / 1200 / 1600 DPI
    • Added next / previous buttons

    1. Anker 2.4G Wireless Vertical Ergonomic Optical Mouse

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    Here you have a practical vertical mouse that would change the way you scroll forever – the Anker 2.4 Wireless Vertical Mouse. It is optical to make your scrolling easier than ever before and even more precise.


    • Wireless Connectivity Technology using USB-port and Bluetooth communication protocols
    • Optical movement detection technology
    • Right-hand orientation technology.
    • It is made from a quality soft plastic material.
    • It has 800/1200/1600 DPI.

    Who is it Best for?

    The current mouse is best for young gamers who like to be online all day. The mouse can help them complete their fine moves to the game and become natural winners. 

    It is also ideal for people who like to have an economy to their electric bill. The mouse saves you energy for the same amount of time spent online.

    Another age group would be the ones that are over 65 years old and need to have fewer movements to their wrists. The mouse helps them scroll a lot easier and creates better conditions if they recover from a local surgery.

    Key Features

    This product has an ergonomic design to make you love it. It is wireless, using a simple USB-adapter to communicate with your desktop or laptop.

    Apart from that, it uses an AAA rechargeable battery you can find in any convenience store.

    Anker is a world-renowned company, present in more than 40 countries. The mouse is compatible with all versions of Windows, Linux, and iOS.


    • A lightweight device
    • Good optical mouse accuracy
    • Enough buttons
    • 18-month hassle-free guarantee.
    • Comfortable design


    • The mouse only comes in black color.

    2. Jelly Comb Advanced Vertical Mouse 2.4GHz

    Jelly Comb Advanced Vertical Mouse 2.4GHz


    • Remote Connectivity through USB, Bluetooth, Radio Frequency.
    • It comes only in Black Color.
    • Jelly Comb brand for extra quality assurance.
    • Right-hand orientation.
    • Optical Movement Detection Technology.

    Who is it Best for?

    The current mouse is best for right-handed people who want to have a complete day at the office without getting their wrists tired. 

    This model can give them more liberty to scroll on pages and even play games when they find the time.

    It is suitable for all people who want to press joint buttons on a game or a presentation. 

    The glove-like size can give it enormous possibilities and an anatomic feature that you will not easily find in other models.

    The two buttons are symmetrically placed around your thumb and fingers to allow you better mouse control.

    Key Features

    The Jelly Comb Advanced Wireless Mouse remains one of the basic gaming tools for teenagers and people who want to scroll on pages faster than others.

    The adjustable DPI can make you have more accuracy when you click on certain spots of a website.

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    The mouse is quite compatible with all computer settings and every operating system you may find.

    You also get a silent click technology that will make you forget that you actually use your mouse.

    The Bluetooth connection through the USB-port will never interfere with any other system you have connected at the same time.


    • Made of smooth plastic
    • Easy to scroll
    • Lifetime guarantee included
    • Two AAA batteries
    • Switch connection mode


    • It takes a lot of space
    • A bit more expensive

    3. Jelly Comb Wireless Mouse 2.4G

    Jelly Comb Wireless Mouse 2.4G

    It has been an efficient vertical mouse model for women, who have smaller hands than other users. 

    Jelly Comb has been the most reputable company in computer peripherals around the world. 

    Many vertical gaming mice that come from this company will be around for years serving you.


    • It has wireless optical technology.
    • There is a right-hand orientation.
    • The scroll button is conveniently placed in the center.
    • The USB connector is smaller than you ever thought.

    Who is it Best for?

    This gaming vertical mouse is better for women, or generally, people with smaller hands. The Jelly Comb Wireless Mouse 2.4G High Precision Ergonomic is always good for gamers who are novice users.

    It can introduce them to the gaming world, giving them an immediate reaction to game challenges and scrolling around with care.

    The mouse is also good for people with wrist issues and carpal syndrome that want to have the least amount of pressure on their hands when they play an online game or just surf online.

    Key Features

    This optical vertical mouse has 2 AAA batteries to work efficiently. It can save energy while being on, and it also has an automatic shut off if left without any movement for more than an hour.

    The left and right-click buttons are conveniently placed by the side of the mouse parts. The scroll button is always on the right to give you the best available control.

    It communicates using the Bluetooth protocol, and anyone can easily find a USB connection that you can replace easily and affordably.


    • Superior ergonomic experience
    • Adjustable DPI settings
    • Smoother hand movements
    • Excellent hand protection
    • Great endurance
    • High responsiveness


    • Not available in all countries
    • No long-term guarantee

    4. Evoluent VM4R Vertical Mouse

    Evoluent VM4R Vertical Mouse

    Here you have one of the most revolutionary vertical gaming mice in the world. The Evoluent VMR4 Vertical Mouse keeps on being easy to handle and acute to its reactions.

    It has been one of the first mice on the market to connect both Mac and Windows computers. The wire connection gives more stability than the remote one.

    The current model also has optical technology to replace the older mouse balls and offer you higher precision and better clicking on any site.


    • USB connectivity for better communications.
    • It weighs less than 7 ounces.
    • It uses two AA batteries to work properly.
    • It is made for right-handed people.
    • All the buttons are placed symmetrically.

    Who is it Best for?

    The model is best for gamers who want to have cable access to their computer when playing.

    It has been the first vertical gaming mouse to replace the older joysticks and give a new perspective to potential games.

    It has a higher movement sensitivity and can be the expansion of your hand on the screen. The response time is one of the lowest existing on the market.

    It is also great for men and women professionals who want to design or plot anything online. The vertical mouse can cooperate with any software and give them increased hand and wrist relaxation while working.

    Key Features

    This model features some thumb buttons to make it easier for you to grab it and perform clicks.

    It looks like a small stone that embraces and follows the curves a normal human hand creates when it’s relaxed.

    The pointer speed lights are always on to give you a clue about the direction.

    It also has a wide lip to deal with rubbing your desk. Also, the hyper scrolling button is more sensitive than ever before.


    • Better eye comfort
    • Easy copy-paste function
    • Relaxed hand position
    • High-ranked product


    • USB cable is not durable

    5. Kensington Ergonomic Vertical Wireless Mouse 

    Kensington Ergonomic Vertical Wireless Mouse

    Here you have the vertical MMO mouse to give you full control over your gaming when you are online.

    Kensington Ergonomic Vertical Mouse is affordable and revolutionary in terms of shape and weight.

    It is one of the few vertical gaming mice that give you immediate action on your screen and remain intact even after years of daily use.


    • It requires only one AA battery to work.
    • Its weight is less than 7 ounces.
    • It belongs to Kensington -a reputable manufacturer.
    • The mouse has a nano receiver storage for the USB connector.

    Who is it Best for?

    The mouse is best for gamers who want to invest a mediocre amount of money in playing their online games effectively.

    If you are a freelancer and specialize in web design and landing pages, that vertical mouse can make it easier for you to plot online and increase your average online time without resting.

    The current mouse is also great for people with movement disorders that need to have a vertical mouse with no muscle contraction requirements.

    Key Features

    The mouse is the absolute plug and play device that has more than 33 feet of connectivity range.

    The angled slop can help you keep your wrist and hand to the handshake position, alleviating pain from constant mouse use.

    The mouse has six buttons, including left, right, forward, backward, and scroll. It can withstand pressure from your hand for a prolonged time without getting compromised.


    • 2400 DPI sensitivity
    • Auto-sleep function
    • Fast-browsing
    • Extended lip support
    • Fast connectivity


    • Suboptimal grip

    6. TRELC Ergonomic Mouse

    TRELC Ergonomic Mouse

    If you look for the best vertical mouse for gaming, then TRELC Ergonomic Mouse could be the best option.

    Made from soft plastic materials, it fully embraces your hand and follows its natural curves.

    It has been one of the first featuring six different control buttons besides the usual right and left-clicks. 

    The USB communication compartment is easy to place and store after use, to have a complete screen control proposal.


    • It works best for Mac and PCs.
    • It weighs less than 3 ounces.
    • Requires only two AAA batteries to work.
    • On/Off switch to save energy when needed.
    • Variable speed scroll button for extreme precision.

    Who is it Best for?

    The mouse works best for gamers who want to have an independent and efficient way to play their games.

    You can follow the screen action simply by moving your hand in the right direction. The mouse has a high DPI rate transmitting the data to your computer in fractions of the second.

    This mouse is also good for people who have wrist sensitivity and need to work online. It can help designers work a lot more efficiently and ease the pain felt by constant browsing, scrolling, and plotting online.

    Key Features

    The mouse has a 54 degrees vertical angle to follow the right anatomy of the human hand.

    Thus, it reduces strain to your wrist and makes your online job a lot easier than it used to be.

    The high precision control can reach up to 2400 DPI, which is the best performance an optical system can deliver today.

    You have the chance to plug the device into your PC and let it play without any driver’s installation.

    Finally, the six-buttons technology can give you the chance to perform any online task without using your keyboard at all.


    • Nano USB receiver
    • Durable material
    • Easily swappable speed
    • Automatic power off mode


    • Cannot be found in all countries

    7. Razer Basilisk Ultimate Gaming Mouse

    Razer Basilisk Ultimate Gaming Mouse

    Here you have the best vertical mouse for gaming that supports all kinds of software and hardware requirements.

    The Razer Basilisk Ultimate remains one of the most innovative models giving you extreme scrolling power and increased style when playing.

    It is one of the few vertical mice that take the physical shape of a basilisk lizard and give you more than 11-buttons options to forget about your keyboard.


    • Its size is less than 11 square inches fitting on all desks.
    • It weighs only 15 ounces.
    • It comes with a lithium battery that is included.
    • There is a charging dock to keep it always full of energy.

    Who is it Best for?

    The current model is the number one vertical mouse for gamers who love to show off to their online friends.

    It has a high DPI rate reaching more than 2400, giving you a remarkable speed close to reality.

    Other people who can benefit from this mouse could spend many hours in front of their screen.

    Doctors, secretaries, and architects who work with their PCs filling in forms all plotting objects can benefit from this model that requires the least muscle contraction from their hands.

    It would also be useful to people who have wrist wounds and surgeries and need to keep their hand in the handshake position when online or working on their computer.

    Key Features

    This vertical mouse has 11 different switches and buttons to keep you completely independent from your keyboard.

    The charging port is easy to connect and can give you full support when playing online games (they drain your wireless mouse battery).

    The optical sensor is sensitive enough to allow the immediate transfer of data from your hand to the computer.

    It has a perfect switch to keep it off when you don’t need it anymore and save battery.


    • A lot of buttons
    • USB or Bluetooth connection
    • Great battery
    • Easy to change sensitivity


    • More expensive than competitors

    8. LEKVEY Vertical Wireless Mouse

    LEKVEY Vertical Wireless Mouse

    Another vertical gaming mouse will give you enormous chances to play online games with extreme speed and quality.

    The LEKVEY Vertical Wireless Mouse is made of high-quality plastic material that is smooth to touch and perfectly ergonomic.

    The vertical mouse eases any pain felt from your wrist and hands area while giving you the chance to communicate right away with your PC, without even touching the keyboard.


    • It weighs only 3.6 ounces.
    • It takes less than 9 square inches of space on your desk.
    • You have the chance to use it with any available OS.
    • It comes in black sapphire color.
    • It has wireless USB technology with a high DPI rate.

    Who is it Best for?

    The vertical mouse is best for novice gamers who want to have a reliable mouse to play their games accurately and with decent speed.

    You can also use it if you belong to the professionals’ team when many manuscripts need to be filled in, or you are a web-designer plotting on your screen all day long.

    People suffering from their wrists and hands can also use it for browsing and online tasks since it needs less effort to operate than usual mice.

    Key Features

    This vertical mouse model has a 58 degrees angle to follow the natural curves of the human hand. It also has four ready to go and easy to click buttons to give you full control of your computer.

    The optical communication protocol works better and can reach up to 1600 DPI that is more than enough for the median user.

    It has a small AA battery to operate, and in the same spot, you may also hide the USB connector so that you don’t lose it.

    Finally, you get the best customer service available online with multiple people on the call center to help you any time of the day.


    • Multifunctional use
    • Good DPI rate
    • Great compatibility
    • Noiseless buttons
    • Best anti-slip grip


    • Battery could be better

    9. TRELC Ergonomic Mouse

    TRELC Ergonomic Mouse

    TRELC company has finally made it to provide you with the best vertical gaming mouse of all time. 

    The TRELC Ergonomic Mouse 10000 DPI is the only model that has 11 adjustable buttons to control almost anything on your screen.

    It has the highest optical system sensitivity with more than 10000 DPI, an impressive number to mention.

    Let’s look at some of the specifications the current model carries, and we proud of them.


    • It has 11 buttons you can program by desire.
    • The roller life has 1.2 million rotation cycles.
    • The product weighs only 165 grams.
    • The return rate can come up to 10K Hz.
    • The USB cable length is almost 1.8 meters.
    • There is an optical traction control with 100mA power.

    Who is it Best for?

    This vertical mouse is the ultimate relic for gamers. It has been made for quick action games that need precision and speed.

    You can use it to play any kind of online game and alter the sequence and function of buttons according to the game needs.

    People who face wrist problems and injuries can also use it. It could be useful to professionals who are all day long in front of their screens and want to draw straight or curved lines.

    Key Features

    This vertical mouse has a direction rocker that gives you an ultimate thumb control.

    The durable click button can give you up to 5 million clicks with the same ease and efficiency.

    It has a 128Kb onboard memory making it easy to perform moves online with speed and accuracy.

    The scroll wheel button is at the right side to let your big finger use it. It is also speed-sensitive to give you maximum performance when being online.


    • Ergonomic shape
    • Features thumb lever
    • RGB lighting
    • 12-month guarantee
    • Easy to use


    • Mat protective film

    Buying a Vertical Mouse for Gaming

    Things to Consider

    It would be better to know more about the best vertical gaming mouse before you finally buy one.

    These are the things you should consider before taking your final decision and order one.


    Most of the vertical mice have an average size that is larger than the usual ones.

    However, when you want to buy an optical vertical mouse, look at the specifications and try to get the ones that are small and gentle.

    The mouse needs to fit into your hand and follow your movements around the pad. 


    Connectivity is also a major feature. Most of the vertical optical mouse models use Bluetooth connectivity. 

    Some others have a USB-component that can attach to your laptop or desktop computer and give it radio frequency signals.

    Both communication ports are plausible, and you need to find the one having the best and fasters data transmission.

    Anatomical Comfort

    It would be better for your upright gaming mouse to have an anatomic shape. That is the one following the natural curves of your hand.

    If you can keep it in your hand and perform all the moves you like on the screen, it’s the right tool for you without getting tired.

    Hardware Compatibility

    Another reason to opt for a vertical mouse for gaming would be the hardware compatibility. Some of them are going well with Apple computers, and some deny cooperating with them.

    It would be best to find the vertical gaming mice that give you higher compatibility with Windows or Linux and guarantee the best work model no matter what software your computer is running.

    Buttons Position

    The most prominent gaming vertical mouse models are the ones that have the left and right-click buttons to the right place.

    Symmetrical buttons are always good to be present on these devices. The scroll button’s place is also important to be close to your big finger and becomes the most important aspect of your comfort when buying a new mouse.


    Finally, performance is measured by the DPI communication speed. That gives you a rough estimate of the data transmitted per second.

    You would like to have a vertical gaming mouse that has the highest DPI rate among others.

    That will give you the chance to enter online games and become a successful player since all your movements will be immediate.


    The best gaming vertical mouse is the one that fits better in your hand and aggravates your movements a lot less than others.

    It would be plausible if you could touch on most of the newest models to know which is the best for your case.

    Ensure that you read the reviews of gamers who have previously used the model you think about buying.

    Being cautious about new releases is always a good tip. If you want to be a top player, then you should carefully check your vertical mouse!

    Frequently Asked Questions

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